Reagent Kit HemeScreen® HRM Screening WT1 For use with HRM-enabled RT-PCR Machine / Cytopenia Panel 100 Tests
Precipio’s HemeScreen® offerings are Research Use Only (RUO) assays that screen for clinically actionable somatic mutations in targets of interest related to myeloproliferative disorders and haematological cancers
Product Specifications
Description
The reagents are designed to be used in a clinical diagnostic laboratory by suitably trained personnel testing DNA extracted from whole blood or bone marrow using a PCR-based method and High Resolution Melt (HRM) Analysis
WT1 (Wilms’ Tumor 1) can lead to higher relapse rate and poor prognosis in patients with acute myeloid leukemia (AML)
WT1 mutations may be observed in 6-15% of AML cases, often with patients who have FLT3-ITD and/or CEBPA mutations
WT1 mutations can be used as a tool in determining MRD
Machine required HRM-enabled RT-PCR (example/ ThermoFisher Quantstudio 3 or higher)
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