Reagent Kit HemeScreen® HRM Screening FLT3 For use with HRM-enabled RT-PCR Machine / AML Panel 100 Tests
Precipio’s HemeScreen® offerings are Research Use Only (RUO) assays thatscreen for clinically actionable somatic mutations in targets of interest related to myeloproliferative disorders and haematological cancers
Product Specifications
Description
The reagents are designed to be used in a clinical diagnostic laboratory by suitably trained personnel testing DNA extracted from whole blood or bone marrow using a PCR-based method and High Resolution Melt (HRM) Analysis
High Resolution Melting (HRM) is a screening technique, which allows the user to determine if the PCR fragment contains a variant or not based upon the dissociation of double-stranded DNA in the presence of an intercalating dye as the temperature increases
FLT3 (fms-like tyrosine kinase) mutation is an unfavorable prognostic marker - FLT3 inhibitors are often paired with chemotherapy for treatment
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